DNMT3A Antikörper
Kurzübersicht für DNMT3A Antikörper (ABIN6943093)
Target
Alle DNMT3A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human
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Aufreinigung
- Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
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Immunogen
- Polyclonal antibody raised in rabbit against human DNMT3A, (DNA methyltransferase 3A), using a KLH-conjugated synthetic peptide corresponding to amino acids 44-58
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anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 457-486) antibody
DNMT3A Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal RB01852 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 500-700) antibodyDNMT3A Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 46-180) antibodyDNMT3A Reaktivität: Human IHC, ELISA, FACS Wirt: Maus Monoclonal 4G5F11 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 26-100) antibodyDNMT3A Reaktivität: Human FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 457-486) antibodyDNMT3A Reaktivität: Human, Maus WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 1-912) antibodyDNMT3A Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 31-61), (N-Term) antibodyDNMT3A Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB15267 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 723-752), (C-Term) antibodyDNMT3A Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB12504 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 705-908), (C-Term) antibodyDNMT3A Reaktivität: Human, Maus WB, IHC, ICC, ChIP Wirt: Maus Monoclonal 64B1446 unconjugated
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) antibodyKO Validated DNMT3A Reaktivität: Human WB, IP Wirt: Kaninchen Monoclonal unconjugated
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Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IP(1-2 μg)
ChIP-seq() -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.75 μg/μL
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Buffer
- PBS with 0.05 % sodium azide and 0.05 % Proclin300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
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Andere Bezeichnung
- DNMT3A
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Hintergrund
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Synonyms: DNMT3A2, TBRS
Background: Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18. Recruited to trimethylated 'Lys-36' of histone H3 (H3K36me3) sites. Can actively repress transcription through the recruitment of HDAC activity.
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Gen-ID
- 1788
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UniProt
- Q9Y6K1
Target
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