CEP290 Antikörper (AA 131-230) (Cy5)
Kurzübersicht für CEP290 Antikörper (AA 131-230) (Cy5) (ABIN6942539)
Target
Alle CEP290 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 131-230
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Kreuzreaktivität
- Maus
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Homologie
- Human,Rat,Dog,Cow,Sheep,Horse
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human CEP290
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- CEP290 (Centrosomal Protein 290kDa (CEP290))
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Andere Bezeichnung
- CEP290
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Hintergrund
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Synonyms: 3H11AG, Bardet-Biedl syndrome 14 protein, BBS14, Cancer/testis antigen 87, CE290_HUMAN, Centrosomal protein 290 kDa, Centrosomal protein of 290 kDa, Cep290, CT87, CTCL tumor antigen se2 2, FLJ13615, FLJ21979, JBTS5, JBTS6, KIAA0373, LCA10, Meckel syndrome, type 4, MKS4, Monoclonal, 3H11 antigen, Nephrocystin 6, Nephrocystin-6, NPHP6, POC3, POC3 centriolar protein homolog, Prostate cancer antigen T21, rd16, SLSN6 1, 2, 5, SLSN6, Tumor antigen se2-2.
Background: This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer. [provided by RefSeq, Jul 2008
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Gen-ID
- 80184
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UniProt
- O15078
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Pathways
- cAMP Metabolic Process, M Phase
Target
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