CEP290 Antikörper (AA 131-230) (AbBy Fluor® 647)

Produktnummer ABIN6942535

Der Kaninchen Polyklonal Anti-CEP290-Antikörper wurde für IF (cc) und IF (p) validiert. Er ist geeignet, CEP290 in Proben von Maus zu detektieren.

Kurzübersicht für CEP290 Antikörper (AA 131-230) (AbBy Fluor® 647) (ABIN6942535)

Target: CEP290 (Centrosomal Protein 290kDa (CEP290))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CEP290 Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CEP290 Antikörper (AbBy Fluor® 647)

Bindungsspezifität: AA 131-230

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CEP290

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CEP290

Target: CEP290 (Centrosomal Protein 290kDa (CEP290))

Andere Bezeichnung: CEP290

Hintergrund:

Synonyms: 3H11AG, Bardet-Biedl syndrome 14 protein, BBS14, Cancer/testis antigen 87, CE290_HUMAN, Centrosomal protein 290 kDa, Centrosomal protein of 290 kDa, Cep290, CT87, CTCL tumor antigen se2 2, FLJ13615, FLJ21979, JBTS5, JBTS6, KIAA0373, LCA10, Meckel syndrome, type 4, MKS4, Monoclonal, 3H11 antigen, Nephrocystin 6, Nephrocystin-6, NPHP6, POC3, POC3 centriolar protein homolog, Prostate cancer antigen T21, rd16, SLSN6 1, 2, 5, SLSN6, Tumor antigen se2-2.

Background: This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer. [provided by RefSeq, Jul 2008

Gen-ID: 80184

UniProt: O15078

Pathways: cAMP Metabolic Process, M Phase