CDK5 Antikörper (AA 31-130) (Biotin)

Produktnummer ABIN6942493

Produktdetails anti-CDK5 Antikörper (Biotin)

Target: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Bindungsspezifität: AA 31-130

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK5 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CDK5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu CDK5

Target: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Andere Bezeichnung: CDK5 (CDK5 Produkte)

Synonyme: PSSALRE antikoerper, AW048668 antikoerper, Crk6 antikoerper, CDK5 antikoerper, CG8203 antikoerper, DmCdk5 antikoerper, Dmel\\CG8203 antikoerper, cdk5 antikoerper, zgc:101604 antikoerper, cyclin dependent kinase 5 antikoerper, cyclin-dependent kinase 5 antikoerper, Cyclin-dependent kinase 5 antikoerper, cyclin-dependent kinase 5 L homeolog antikoerper, Cyclin-dependent-like kinase 5 antikoerper, CDK5 antikoerper, Cdk5 antikoerper, cdk5 antikoerper, cdk5.L antikoerper, cdk-5 antikoerper

Hintergrund:

Synonyms: Cdk 5, Cell division protein kinase 5, Crk6, Cyclin dependent kinase 5, Protein kinase CDK5 splicing, PSSALRE, Serine threonine protein kinase PSSALRE, Tau protein kinase II catalytic subunit, TPKII catalytic subunit.

Background: This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]

Gen-ID: 1020

UniProt: Q00535

Pathways: Zellzyklus, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis