Caspase 2 Antikörper (AA 150-350)
Kurzübersicht für Caspase 2 Antikörper (AA 150-350) (ABIN6942345)
Target
Alle Caspase 2 (CASP2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 150-350
-
Verwendungszweck
- Caspase 2 (2B1) Monoclonal Antibody
-
Kreuzreaktivität
- Human, Maus, Ratte
-
Aufreinigung
- Purified by Protein A.
-
Immunogen
- Recombinant human Caspase-2 between 150 to 350 amino acids
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB(1:500-2000), FCM(1:100-500), IHC-P(1:200-500), IF(IHC-P)(1:100-500), IF(ICC)(1:50-200)
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C for 12 months.
-
Haltbarkeit
- 12 months
-
-
- Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
-
Andere Bezeichnung
- CASP2
-
Hintergrund
-
Synonyms: Caspase-2, Neural precursor cell expressed developmentally down-regulated protein 2, Protease ICH-1, CASP-2, NEDD-2, Caspase-2 subunit p18
Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. Associates with PIDD1 and CRADD to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis in response to genotoxic stress.
-
Gen-ID
- 835
-
UniProt
- P42575
-
Pathways
- Apoptose, Caspase Kaskade in der Apoptose, Neurotrophin Signalübertragung
Target
-