BAZ1B Antikörper
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- Target Alle BAZ1B Antikörper anzeigen
- BAZ1B (Bromodomain Adjacent To Zinc Finger Domain, 1B (BAZ1B))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser BAZ1B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS)
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- Recombinant protein within C-terminal human BAZ1B.
- Klon
- 5G1
- Isotyp
- IgG
- Top Product
- Discover our top product BAZ1B Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
FCM 1:20-100 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- BAZ1B (Bromodomain Adjacent To Zinc Finger Domain, 1B (BAZ1B))
- Andere Bezeichnung
- BAZ1B (BAZ1B Produkte)
- Synonyme
- BAZ1B antikoerper, wstf antikoerper, wbscr9 antikoerper, wbscr10 antikoerper, LOC100220420 antikoerper, WBSCR10 antikoerper, WBSCR9 antikoerper, WSTF antikoerper, C87820 antikoerper, Wbscr9 antikoerper, fi60d02 antikoerper, im:7137554 antikoerper, wu:fi60d02 antikoerper, bromodomain adjacent to zinc finger domain 1B antikoerper, bromodomain adjacent to zinc finger domain, 1B antikoerper, bromodomain adjacent to zinc finger domain 1B S homeolog antikoerper, BAZ1B antikoerper, baz1b antikoerper, Baz1b antikoerper, baz1b.S antikoerper
- Hintergrund
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Synonyms: Tyrosine-protein kinase BAZ1B, Bromodomain adjacent to zinc finger domain protein 1B, Williams syndrome transcription factor, Williams-Beuren syndrome chromosomal region 10 protein, Williams-Beuren syndrome chromosomal region 9 protein, hWALp2, BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF
Background: Atypical tyrosine-protein kinase that plays a central role in chromatin remodeling and acts as a transcription regulator. Involved in DNA damage response by phosphorylating 'Tyr-142' of histone H2AX (H2AXY142ph). H2AXY142ph plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription, mediates the histone H2AX phosphorylation at 'Tyr-142', and is involved in the maintenance of chromatin structures during DNA replication processes. In the complex, it mediates the recruitment of the WICH complex to replication foci during DNA replication.
- Gen-ID
- 9031
- UniProt
- Q9UIG0
- Pathways
- Nuclear Hormone Receptor Binding, Chromatin Binding
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