Angiopoietin 2 Antikörper (AA 200-350)
Kurzübersicht für Angiopoietin 2 Antikörper (AA 200-350) (ABIN6942114)
Target
Alle Angiopoietin 2 (ANGPT2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 200-350
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Verwendungszweck
- Angiopoietin 2 (4G2) Monoclonal Antibody
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- Purified by Protein A.
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Immunogen
- Human Angiopoietin 2 aa 200-350
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Isotyp
- IgG
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Applikationshinweise
- WB(1:300-5000), IHC-P(1:200-400)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- Angiopoietin 2 (ANGPT2)
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Andere Bezeichnung
- ANGPT2
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Hintergrund
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Synonyms: Angiopoietin-2, ANG-2, ANGPT2.
Background: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
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Gen-ID
- 285
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UniProt
- O15123
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Pathways
- RTK Signalweg
Target
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