Rekombinanter Cytokeratin 2 Antikörper

Produktnummer ABIN6941456

Der Kaninchen Monoklonal anti-Cytokeratin 2 Antikörper (Klon KRTH-1576R) (ABIN6941456) detektiert spezifisch Cytokeratin 2 in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Hund.

Kurzübersicht für Rekombinanter Cytokeratin 2 Antikörper (ABIN6941456)

Target: Cytokeratin 2 (KRT76) (Cytokeratin-2P (KRT76))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Hund

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Cytokeratin 2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: KRTH-1576R

Produktdetails anti-Cytokeratin 2 Antikörper

Verwendungszweck: Recombinant Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) Antibody

Spezifität: This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67 kDa (CK1), 64 kDa (CK3), 59 kDa (CK4), 58 kDa (CK5), 56 kDa (CK6), 52 kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40 kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52 kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

Kreuzreaktivität (Details): Expected to show broad species reactivity.

Aufreinigung: 200ug/ml of recombinant MAb Purified by Protein A/G.

Immunogen: Recombinant full-length human KRT76 protein

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Epithelial cells, Skin or Adenocarcinomas.

Known Application: Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Cytokeratin 2

Target: Cytokeratin 2 (KRT76) (Cytokeratin-2P (KRT76))

Andere Bezeichnung: KRT76

Hintergrund:

KRT2B, KRT2P, HUMCYT2A, Keratin, type II Cytoskeletal 2 oral, K76, Keratin 2p (K2P), Keratin-76, Cytokeratin-2P (CK-2P, Type-II Keratin Kb9

Epithelial cells, Skin or Adenocarcinomas.

Molekulargewicht: 52-67kDa

Gen-ID: 51350, 654392

UniProt: Q01546