Cytokeratin 2 Antikörper

Produktnummer ABIN6941449

Der Maus Monoklonal anti-Cytokeratin 2 Antikörper wird verwendet zum Nachweis von Cytokeratin 2 in Proben von Human und Ratte. Er wurde validiert für IHC.

Kurzübersicht für Cytokeratin 2 Antikörper (ABIN6941449)

Target: Cytokeratin 2 (KRT76) (Cytokeratin-2P (KRT76))

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cytokeratin 2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: KRTH-1076

Produktdetails anti-Cytokeratin 2 Antikörper

Verwendungszweck: Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) Antibody

Spezifität: This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40kDa. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

Kreuzreaktivität (Details): Shows broad species reactivity.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human KRT76 protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Skin, Adenocarcinomas.

Known Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Cytokeratin 2

Target: Cytokeratin 2 (KRT76) (Cytokeratin-2P (KRT76))

Andere Bezeichnung: KRT76

Hintergrund: Adenocarcinomas., Skin

Molekulargewicht: 67kDa (CK1), 64kDa (CK3), 59kDa (CK4), 58kDa (CK5), 56kDa (CK6), 52kDa (CK8)

Gen-ID: 51350, 654392

UniProt: Q01546