CD70 Antikörper
Kurzübersicht für CD70 Antikörper (ABIN6941251)
Target
Alle CD70 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- It recognizes a protein of 30 kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.
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Aufreinigung
- Purified by Protein A/G
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Immunogen
- Recombinant human CD70 protein
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Isotyp
- IgG1 kappa
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Applikationshinweise
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Positive Control: Raji cells. Lymph node or tonsil.
Known Application: ELISA (For coating, order Ab without BSA), Functional Studies (Order Ab without Azide), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Frozen) (0.5-1 μg/mL for 30 minutes at RT),Optimal dilution for a specific application should be determined.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- 10mM PBS with 0.05% BSA & 0.05% azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Haltbarkeit
- 24 months
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- CD70 (CD70 Molecule (CD70))
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Andere Bezeichnung
- CD70
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Molekulargewicht
- 30kDa
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Gen-ID
- 970
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UniProt
- P32970
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Pathways
- Cancer Immune Checkpoints
Target
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