Rekombinanter NAPSA Antikörper (AA 189-299)

Produktnummer ABIN6941166

Der Kaninchen Monoklonal anti-NAPSA Antikörper wird verwendet zum Nachweis von NAPSA in Proben von Human, Ratte und Kaninchen. Er wurde validiert für IHC und WB.

Kurzübersicht für Rekombinanter NAPSA Antikörper (AA 189-299) (ABIN6941166)

Target: NAPSA (Napsin A Aspartic Peptidase (NAPSA))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Ratte, Kaninchen

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser NAPSA Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Klon: NAPSA-1865R

Produktdetails anti-NAPSA Antikörper

Bindungsspezifität: AA 189-299

Verwendungszweck: Recombinant Napsin A (Lung Adenocarcinoma Marker) Antibody

Spezifität: Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B.There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.

Aufreinigung: 200ug/ml of recombinant MAb Purified by Protein A/G.

Immunogen: Recombinant human Napsin-A protein fragment (aa189-299) (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Lung adenocarcinoma.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu NAPSA

Target: NAPSA (Napsin A Aspartic Peptidase (NAPSA))

Andere Bezeichnung: NAPSA

Hintergrund:

ASP4, Aspartyl protease 4, KAP, Kidney derived aspartic protease like protein (Kdap), NAP1, NAPA, Napsa, napsin A aspartic peptidase, Pronapsin A, SNAPA

Lung adenocarcinoma, Lung, Kidney, K-562, HEK293, A549, Human Brain, Human Heart, Human Intestine, Human Kidney, Human Liver, Human Lung, Human Ovary, Human Pancreas, Human Prostrate, Human Skeletal Muscle, Human Skin, Human Spleen, Human Stomach, Human Testis

Molekulargewicht: 37kDa

Gen-ID: 9476, 512843

UniProt: O96009

Pathways: Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis