Rekombinanter CD27 Antikörper
Kurzübersicht für Rekombinanter CD27 Antikörper (ABIN6941126)
Target
Alle CD27 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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                                            Spezifität
- Recognizes a protein of a disulfide-linked 120 kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFkB and SAPK/JNK and induces apoptosis.
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                                            Aufreinigung
- Purified by Protein A/G
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                                            Immunogen
- Recombinant human full-length CD22 protein (exact sequence is proprietary)
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                                            Isotyp
- IgG
 
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                                            Applikationshinweise
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                        Positive Control: Human peripheral blood lymphocytes. Human tonsil and lymph node. Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined. 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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                                            Konzentration
- 200 μg/mL
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                                            Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Lagerung
- 4 °C,-80 °C
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                                            Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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                                            Haltbarkeit
- 24 months
 
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    - CD27 (CD27 Molecule (CD27))
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                                            Andere Bezeichnung
- CD27
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                                            Molekulargewicht
- 120kDa
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                                            Gen-ID
- 939
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                                            UniProt
- P26842
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                                            Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
 Target
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