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Rekombinanter CD27 Antikörper

This anti-CD27 antibody (ABIN6941126) is a Rabbit Monoclonal antibody detecting CD27 in IHC, StM. Suitable for Human.
Produktnummer ABIN6941126

Quick Overview for Rekombinanter CD27 Antikörper (ABIN6941126)

Target

Alle CD27 Antikörper anzeigen
CD27 (CD27 Molecule (CD27))

Antikörpertyp

Recombinant Antibody

Reaktivität

  • 212
  • 77
  • 56
  • 9
  • 5
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 120
  • 96
  • 22
  • 11
  • 3
  • 3
  • 2
  • 1
Kaninchen

Klonalität

  • 155
  • 101
  • 2
Monoklonal

Konjugat

  • 95
  • 26
  • 25
  • 16
  • 15
  • 7
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CD27 Antikörper ist unkonjugiert

Applikation

  • 165
  • 91
  • 53
  • 49
  • 38
  • 30
  • 20
  • 18
  • 14
  • 13
  • 13
  • 9
  • 6
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Staining Methods (StM)

Klon

LPFS2-2034R
  • Spezifität

    Recognizes a protein of a disulfide-linked 120 kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFkB and SAPK/JNK and induces apoptosis.

    Aufreinigung

    Purified by Protein A/G

    Immunogen

    Recombinant human full-length CD22 protein (exact sequence is proprietary)

    Isotyp

    IgG
  • Applikationshinweise

    Positive Control: Human peripheral blood lymphocytes. Human tonsil and lymph node.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    200 μg/mL

    Buffer

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-80 °C

    Informationen zur Lagerung

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    Haltbarkeit

    24 months
  • Target

    CD27 (CD27 Molecule (CD27))

    Andere Bezeichnung

    CD27

    Molekulargewicht

    120kDa

    Gen-ID

    939

    UniProt

    P26842

    Pathways

    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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