Rekombinanter CD27 Antikörper
Quick Overview for Rekombinanter CD27 Antikörper (ABIN6941126)
Target
Alle CD27 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Spezifität
- Recognizes a protein of a disulfide-linked 120 kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFkB and SAPK/JNK and induces apoptosis.
-
Aufreinigung
- Purified by Protein A/G
-
Immunogen
- Recombinant human full-length CD22 protein (exact sequence is proprietary)
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
Positive Control: Human peripheral blood lymphocytes. Human tonsil and lymph node.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 200 μg/mL
-
Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-80 °C
-
Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
Haltbarkeit
- 24 months
-
-
- CD27 (CD27 Molecule (CD27))
-
Andere Bezeichnung
- CD27
-
Molekulargewicht
- 120kDa
-
Gen-ID
- 939
-
UniProt
- P26842
-
Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
Target
-