CD2 Antikörper

Produktnummer ABIN6941011

Der Maus Monoklonal Anti-CD2-Antikörper wurde für FACS, IF, WB und Func validiert. Er ist geeignet, CD2 in Proben von Human zu detektieren.

Kurzübersicht für CD2 Antikörper (ABIN6941011)

Target: CD2

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Functional Studies (Func)

Klon: 1E7E8-G4

Produktdetails anti-CD2 Antikörper

Aufreinigung: Purified by Protein A/G

Immunogen: Human Thymocytes/Sezary T cells

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: MOLT-4, 293T or Jurkat cells. Lymph node and tonsil.

Known Application: Functional Studies (Order Ab without Azide),Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu CD2

Target: CD2

Andere Bezeichnung: CD2

Hintergrund: CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

Molekulargewicht: 50kDa

Gen-ID: 914

UniProt: P06729