Rekombinanter TIMP1 Antikörper
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- Target Alle TIMP1 Antikörper anzeigen
- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser TIMP1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Coating (Coat)
- Immunogen
- Recombinant full-length human TIMP1 protein
- Klon
- RTIMP1-1710
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product TIMP1 Primärantikörper
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- Applikationshinweise
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Positive Control: 293 cell extract or rat brain lysate. Human colon carcinoma.
Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA),Optimal dilution for a specific application should be determined.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-80 °C
- Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Haltbarkeit
- 24 months
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- Target
- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
- Andere Bezeichnung
- TIMP1 (TIMP1 Produkte)
- Synonyme
- TIMP-1 antikoerper, TIMP1 antikoerper, DKFZp468A0912 antikoerper, CLGI antikoerper, EPA antikoerper, EPO antikoerper, HCI antikoerper, TIMP antikoerper, Timp antikoerper, Clgi antikoerper, TIMP metallopeptidase inhibitor 1 antikoerper, tissue inhibitor of metalloproteinase 1 antikoerper, TIMP1 antikoerper, Timp1 antikoerper
- Hintergrund
- TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases -1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 is identical to EPA (erythroid-potentiation activity). PTH has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart tissues. Studies have demonstrated that TIMP1 is useful as a biomarker for early detection of colorectal cancer, outperforming CEA. Additionally, TIMP1 studies have demonstrated its role in CRC tumorigenesis, as well as observing its overexpression in metastatic lymph nodes.
- Molekulargewicht
- 23kDa
- Gen-ID
- 7076
- UniProt
- P01033
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