TIMP1 Antikörper (AA 131-207)

Produktnummer ABIN707441

Produktdetails anti-TIMP1 Antikörper

Target: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Bindungsspezifität: AA 131-207

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIMP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Sheep,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TIMP-1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu TIMP1

Target: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Andere Bezeichnung: TIMP-1 (TIMP1 Produkte)

Synonyme: TIMP-1 antikoerper, TIMP1 antikoerper, DKFZp468A0912 antikoerper, CLGI antikoerper, EPA antikoerper, EPO antikoerper, HCI antikoerper, TIMP antikoerper, Timp antikoerper, Clgi antikoerper, TIMP metallopeptidase inhibitor 1 antikoerper, tissue inhibitor of metalloproteinase 1 antikoerper, TIMP1 antikoerper, Timp1 antikoerper

Hintergrund:

Synonyms: Clgi, Collagenase inhibitor, EPA, EPO, Erythroid Potentiating Activity, Fibroblast collagenase inhibitor, FLJ90373, HC, Human Collagenase Inhibitor, Metalloproteinase inhibitor 1, Metalloproteinase inhibitor 1 precursor, OTTHUMP00000023214, TIMP 1, TIMP, TIMP metallopeptidase inhibitor 1, TIMP1 protein, Tissue Inhibitor of Metalloproteinase 1, Tissue inhibitor of metalloproteinases, Ttissue inhibitor of metalloproteinase 1 erythroid potentiating activity collagenase inhibitor.

Background: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq].

Molekulargewicht: 23-28kDakDa

Gen-ID: 7076