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Transferrin Receptor Antikörper (AA 94-212)

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Transferrin Receptor in WB, IHC, ELISA, Coat und StM. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN6940699

Kurzübersicht für Transferrin Receptor Antikörper (AA 94-212) (ABIN6940699)

Target

Alle Transferrin Receptor (TFRC) Antikörper anzeigen
Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reaktivität

  • 234
  • 102
  • 40
  • 10
  • 7
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
Human

Wirt

  • 140
  • 131
  • 36
  • 4
  • 1
  • 1
  • 1
Maus

Klonalität

  • 199
  • 109
  • 4
Monoklonal

Konjugat

  • 161
  • 31
  • 24
  • 16
  • 11
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Transferrin Receptor Antikörper ist unkonjugiert

Applikation

  • 173
  • 164
  • 99
  • 70
  • 63
  • 63
  • 48
  • 24
  • 20
  • 11
  • 7
  • 6
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Coating (Coat), Staining Methods (StM)

Klon

TFRC-1817
  • Bindungsspezifität

    • 16
    • 13
    • 12
    • 11
    • 9
    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 94-212

    Spezifität

    It recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

    Aufreinigung

    Purified by Protein A/G

    Immunogen

    Recombinant extracellular fragment (around aa 94-212) of human TFRC protein (exact sequence is proprietary)

    Isotyp

    IgG2b kappa
  • Applikationshinweise

    Positive Control: Jurkat, HeLa, MCF-7 or K562 cells. Human placenta or Bone Marrow.

    Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes) Western Blot (0.5-1.0 μg/mL)Optimal dilution for a specific application should be determined.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    200 μg/mL

    Buffer

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-80 °C

    Informationen zur Lagerung

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    Haltbarkeit

    24 months
  • Target

    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

    Andere Bezeichnung

    TFRC

    Molekulargewicht

    85-95kDa (monomer), 190kDa (dimer)

    Gen-ID

    7037

    UniProt

    P02786

    Pathways

    Transition Metal Ion Homeostasis
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