Transferrin Receptor Antikörper

Produktnummer ABIN6940694

Der Maus Monoklonal Anti-Transferrin Receptor-Antikörper wurde für FACS, WB und IF validiert. Er ist geeignet, Transferrin Receptor in Proben von Human zu detektieren.

Kurzübersicht für Transferrin Receptor Antikörper (ABIN6940694)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Transferrin Receptor Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF)

Klon: DF1513

Produktdetails anti-Transferrin Receptor Antikörper

Spezifität: It recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa (Workshop IV). This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Aufreinigung: Purified by Protein A/G

Immunogen: KG1 acute myeloid leukemia cell line

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: CCRF-CEM, Jurkat or K-562. Human placenta or breast carcinoma.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (0.5-1.0 μg/mL),Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Andere Bezeichnung: TFRC

Molekulargewicht: 85-95kDa (monomer), 190kDa (dimer)

Gen-ID: 7037

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis