Rekombinanter Prolactin Receptor Antikörper

Produktnummer ABIN6940407

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Prolactin Receptor in IHC und StM. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter Prolactin Receptor Antikörper (ABIN6940407)

Target: Prolactin Receptor (PRLR)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Prolactin Receptor Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Staining Methods (StM)

Klon: RPRLR-742

Produktdetails anti-Prolactin Receptor Antikörper

Spezifität: It recognizes a protein of 70 kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant full-length human PRLR protein

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Testicular Carcinoma.

Known Application: Immunohistochemistry (Formalin-fixed. Not suitable for frozen tissues.) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. ,Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Prolactin Receptor

Target: Prolactin Receptor (PRLR)

Andere Bezeichnung: PRLR

Molekulargewicht: 70kDa

Gen-ID: 5618

UniProt: P16471

Pathways: JAK-STAT Signalweg, Response to Growth Hormone Stimulus