RNLS Antikörper (AA 34-235)

Produktnummer ABIN6940382

Dieses Anti-RNLS-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von RNLS in ELISA und Coat. Geeignet für Human.

Kurzübersicht für RNLS Antikörper (AA 34-235) (ABIN6940382)

Target: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RNLS Antikörper ist unkonjugiert

Applikation: ELISA, Coating (Coat)

Klon: RNLS-1940

Produktdetails anti-RNLS Antikörper

Bindungsspezifität: AA 34-235

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant human RNLS protein fragment (around aa 34-235) (exact sequence is proprietary)

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: 293T cells. Heart or Kidney.

Known Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu RNLS

Target: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Andere Bezeichnung: RNLS

Hintergrund: Renalase is a 342 amino acid FAD-dependent amine oxidase that is highly expressed in kidney and is expressed at a lower level in heart, skeletal muscle and small intestine. Renalase is secreted in the blood by the kidney and it is thought to regulate cardiac function and systemic blood pressure. It is also suggested that Renalase functions as a hormone that metabolizes circulating catecholamines, which have an active role in the sympathetic and parasympathetic nervous systems. Individuals with chronic kidney disease and end-stage renal disease have markedly reduced levels of plasma Renalase than healthy individuals. Infusion of Renalase in animal models causes decrease in heart rate, cardiac contractility and blood pressure. Two isoforms of Renalase exist due to alternative splicing events.

Molekulargewicht: 38kDa

Gen-ID: 55328

UniProt: Q5VYX0