RNLS Antikörper (Middle Region)

Produktnummer ABIN2788137

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RNLS in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Pferd, Schwein, Kaninchen, Hund und Meerschweinchen.

Kurzübersicht für RNLS Antikörper (Middle Region) (ABIN2788137)

Target: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Reaktivität: Human, Maus, Ratte, Pferd, Schwein, Kaninchen, Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNLS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RNLS Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: Rnls Antibody - middle region

Sequenz: GMKIGVPWSC RYLSSHPCIC FISIDNKKRN IESSECGPSV VIQTTVPFGV

Homologie: Dog: 79%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Rnls. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59612-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu RNLS

Target: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Andere Bezeichnung: Rnls

Hintergrund:

Background Information: Rnls is a probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. It degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. It lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.

Gene Name: Renalase, FAD-dependent amine oxidase

Alternative Symbols: AI452315, AW060440, C10orf59, 6530404N21Rik

Protein Name: Renalase

Molekulargewicht: 33kDa

Gen-ID: 67795

NCBI Accession: NP_001161290

UniProt: A7RDN6