YBX1 Antikörper

Produktnummer ABIN6940225

Dieses Anti-YBX1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von YBX1 in IHC und StM. Geeignet für Human.

Kurzübersicht für YBX1 Antikörper (ABIN6940225)

Target: YBX1 (Y Box Binding Protein 1 (YBX1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser YBX1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Staining Methods (StM)

Klon: YBX1-2430

Produktdetails anti-YBX1 Antikörper

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant human full-length YBX1 protein

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: MCF-7, HEK293 or PC12 cells. Prostate, Breast or Lung Carcinoma.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu YBX1

Target: YBX1 (Y Box Binding Protein 1 (YBX1))

Andere Bezeichnung: YBX1

Hintergrund: The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Y-box binding protein-1 (YBX1) is the prototypic member of the cold shock protein family that fulfills numerous cellular functions. In the nucleus, YBX1 protein orchestrates transcription of proliferation-related genes, whereas in the cytoplasm it associates with mRNA and directs translation. In human tumor entities, such as breast, lung and prostate cancer, cellular YBX1 expression indicates poor clinical outcome, suggesting that YBX1 is an attractive marker to predict patients' prognosis.

Molekulargewicht: 36kDa

Gen-ID: 4904

UniProt: P67809

Pathways: Regulation of Muscle Cell Differentiation