MYOD1 Antikörper (AA 180-189)
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- Target Alle MYOD1 Antikörper anzeigen
- MYOD1 (Myogenic Differentiation 1 (MYOD1))
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Bindungsspezifität
- AA 180-189
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Reaktivität
- Human, Maus, Ratte, Huhn
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser MYOD1 Antikörper ist unkonjugiert
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Applikation
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (IHC), Staining Methods (StM), Immunostaining (ISt)
- Spezifität
- Recognizes a phosphor-protein of 45 kDa, identified as MyoD1. The epitope of this MAb maps between amino acid 180-189 in the C-terminal of Mouse MyoD1 protein. It does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm's tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing's sarcomas and alveolar soft part sarcomas.
- Aufreinigung
- Purified by Protein A/G
- Immunogen
- Recombinant MyoD of Mouse origin with an epitope mapping to amino acids 180-189.
- Klon
- SPM427
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product MYOD1 Primärantikörper
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- Applikationshinweise
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Positive Control: Rhabdomyosarcoma.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 1 mM EDTA Buffer, pH 7.5-8.5, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-80 °C
- Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Haltbarkeit
- 24 months
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- Target
- MYOD1 (Myogenic Differentiation 1 (MYOD1))
- Andere Bezeichnung
- MYOD1 (MYOD1 Produkte)
- Synonyme
- MYF3 antikoerper, MYOD antikoerper, PUM antikoerper, bHLHc1 antikoerper, MyoD antikoerper, XMyoD antikoerper, XtmyoD antikoerper, mf25 antikoerper, myf3 antikoerper, pum antikoerper, MUF3 antikoerper, AI503393 antikoerper, Myod-1 antikoerper, etID309723.25 antikoerper, myod antikoerper, wu:fb57a01 antikoerper, zgc:136744 antikoerper, MYOD1 antikoerper, myod1 antikoerper, mf1 antikoerper, myod1-a antikoerper, myod1-b antikoerper, myogenic differentiation 1 antikoerper, MYOD protein antikoerper, myogenic factor MyoD1 antikoerper, myogenic differentiation 1 S homeolog antikoerper, myogenic differentiation 1 L homeolog antikoerper, MYOD1 antikoerper, myod1 antikoerper, Myod1 antikoerper, myod antikoerper, myod1.S antikoerper, myod1.L antikoerper
- Molekulargewicht
- 45kDa
- Gen-ID
- 4654
- UniProt
- P15172
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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