MMP2 Antikörper (AA 444-575)
Kurzübersicht für MMP2 Antikörper (AA 444-575) (ABIN6940067)
Target
Alle MMP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 444-575
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Spezifität
- It recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.
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Aufreinigung
- Purified by Protein A/G
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Immunogen
- Recombinant human MMP2 protein fragment (aa 444-575) (exact sequence is proprietary)
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Isotyp
- IgG1 kappa
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Applikationshinweise
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Positive Control: U-138 MG or U-87 MG cells. Placenta or Colon Carcinoma.
Known Application: Western Blot (0.5-1 μg/mL) Optimal dilution for a specific application should be determined.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Haltbarkeit
- 24 months
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- MMP2 (Matrix Metalloproteinase 2 (MMP2))
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Andere Bezeichnung
- MMP2
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Molekulargewicht
- 72kDa (Pro), 63kDa (cleaved)
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Gen-ID
- 4313
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UniProt
- P08253
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Pathways
- Activation of Innate immune Response
Target
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