IFNA1 Antikörper

Produktnummer ABIN6939689

Dieser Maus Monoklonal Antikörper detektiert spezifisch IFNA1 in WB, FACS, IF und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für IFNA1 Antikörper (ABIN6939689)

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IFNA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: Feb-48

Produktdetails anti-IFNA1 Antikörper

Aufreinigung: Purified by Protein A/G

Immunogen: Purified recombinant human IFN-alpha1

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Stimulated human peripheral blood mononuclear cells.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Western Blot (1-2 μg/mL), Immunohistochemistry (frozen), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu IFNA1

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Andere Bezeichnung: IFNA1

Hintergrund: This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

Molekulargewicht: 16-27kDa

Gen-ID: 3439

UniProt: P01562

Pathways: JAK-STAT Signalweg, Hepatitis C