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Endoglin Antikörper (AA 74-251)

This anti-Endoglin antibody (ABIN6939307) is a Mouse Monoclonal antibody detecting Endoglin in WB, IHC, StM. Suitable for Human.
Produktnummer ABIN6939307

Kurzübersicht für Endoglin Antikörper (AA 74-251) (ABIN6939307)

Target

Alle Endoglin (ENG) Antikörper anzeigen
Endoglin (ENG)

Reaktivität

  • 196
  • 71
  • 62
  • 19
  • 10
  • 6
  • 5
  • 3
  • 3
  • 3
  • 2
  • 1
Human

Wirt

  • 133
  • 98
  • 21
  • 3
  • 2
  • 1
Maus

Klonalität

  • 131
  • 126
  • 1
Monoklonal

Konjugat

  • 115
  • 31
  • 26
  • 24
  • 15
  • 7
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Endoglin Antikörper ist unkonjugiert

Applikation

  • 158
  • 156
  • 79
  • 55
  • 49
  • 29
  • 25
  • 25
  • 23
  • 18
  • 13
  • 7
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)

Klon

ENG-3269
  • Bindungsspezifität

    • 16
    • 16
    • 11
    • 11
    • 11
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 74-251

    Aufreinigung

    Purified by Protein A/G

    Immunogen

    Recombinant human Endoglin protein fragment (aa74-251) (exact sequence is proprietary)

    Isotyp

    IgG2b kappa
  • Applikationshinweise

    Positive Control: HeLa, A431 or HL-60 cell lysates (WB). Human tonsil or placenta (IHC).

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    200 μg/mL

    Buffer

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-80 °C

    Informationen zur Lagerung

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    Haltbarkeit

    24 months
  • Target

    Endoglin (ENG)

    Andere Bezeichnung

    ENG

    Hintergrund

    CD105/Endoglin is a Type I membrane glycoprotein located on cell surfaces and is part of the TGF-beta receptor complex. This protein has been found on endothelial cells, activated macrophages, fibroblasts, and smooth-muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. CD105 is highly expressed in endothelial cells during tumor angiogenesis and inflammation, with weak or negative expression in vascular endothelium of normal tissues. Angiogenesis is a promising prognostic marker in a variety of tumors. Endoglin is a more specific and sensitive marker for tumor angiogenesis than CD31 or CD34, as it labels only newly-formed blood vessels and may serve as a prognostic marker for Prostate Adenocarcinoma, and cancers of the lung, stomach, breast, and brain.

    Molekulargewicht

    84kDa

    Gen-ID

    2022

    UniProt

    P17813
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