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BTLA Antikörper

BTLA Reaktivität: Human ELISA, Coat Wirt: Maus Monoclonal BTLA-1528 unconjugated
Produktnummer ABIN6939222
  • Target Alle BTLA Antikörper anzeigen
    BTLA (B and T Lymphocyte Associated (BTLA))
    Reaktivität
    • 59
    • 35
    • 4
    • 2
    • 1
    • 1
    Human
    Wirt
    • 33
    • 28
    • 11
    • 4
    • 1
    • 1
    Maus
    Klonalität
    • 44
    • 32
    • 2
    Monoklonal
    Konjugat
    • 44
    • 7
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BTLA Antikörper ist unkonjugiert
    Applikation
    • 51
    • 44
    • 26
    • 13
    • 13
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Coating (Coat)
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant full-length human BTLA protein
    Klon
    BTLA-1528
    Isotyp
    IgG2b kappa
    Top Product
    Discover our top product BTLA Primärantikörper
  • Applikationshinweise

    Positive Control: Human lymph node or MDAMB468 xenograft.

    Known Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    BTLA (B and T Lymphocyte Associated (BTLA))
    Andere Bezeichnung
    BTLA (BTLA Produkte)
    Synonyme
    BTLA antikoerper, BTLA1 antikoerper, CD272 antikoerper, A630002H24 antikoerper, B and T lymphocyte associated antikoerper, BTLA antikoerper, Btla antikoerper
    Hintergrund
    B and T lymphocyte attenuator (BTLA) is an immunoglobulin domain-containing glycoprotein whose expression is induced during T-cell activation. BTLA is similar to CTLA-4 and PD-1, all of which are coinhibitory receptors belonging to the CD28 family. However, unlike CTLA-4 and PD-1, BTLA does not interact with B7-Ig family counter receptors. Rather, the herpesvirus entry mediator (HVEM), a TNF receptor, acts as a molecular switch that modulates T-cell activation by propagating inhibitory signals through BTLA. The BTLAHVEM interaction is conserved between Mouse and human, suggesting that this system is an important pathway regulating lymphocyte activation.
    Molekulargewicht
    33kDa
    Gen-ID
    151888
    Pathways
    Cancer Immune Checkpoints
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