GPN1 Antikörper

Produktnummer ABIN6939142

Der Maus Monoklonal Anti-GPN1-Antikörper wurde für WB, ELISA und Coat validiert. Er ist geeignet, GPN1 in Proben von Human zu detektieren.

Kurzübersicht für GPN1 Antikörper (ABIN6939142)

Target: GPN1 (GPN-Loop GTPase 1 (GPN1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GPN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Coating (Coat)

Klon: GPN1-2350

Produktdetails anti-GPN1 Antikörper

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant full-length human GPN1 protein

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Pancreas, Testis, Thyroid or Bladder.

Known Application: ELISA (For coating, order antibody without BSA), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu GPN1

Target: GPN1 (GPN-Loop GTPase 1 (GPN1))

Andere Bezeichnung: GPN1

Hintergrund: GPN1 is involved in protein synthesis events. It is expressed ubiquitously with highest expression in testis. It binds to the RNA polymerase II- (Poll II) associated proteins RPAP1-3 and to XPA (a protein involved in DNA repair mechanisms), thereby forming an interface with Poll II. Via this interaction, GPN1 is thought to mediate the involvement of Pol II in both protein complex formation and protein chaperone/ scaffolding activities. In addition, GPN1 interacts with components of the integrator and molecular chaperone complexes, further implicating GPN1 in protein assembly. GPN1 contains a cluster of acidic amino acids in its C-terminal region and a series of sequences similar to those found in GTP-binding proteins in its N-terminal region, suggesting that GPN1 has possible GTPase activity.

Molekulargewicht: 42kDa

Gen-ID: 11321