GPN1 Antikörper

Produktnummer ABIN6937346

Dieser Maus Monoklonal Antikörper detektiert spezifisch GPN1 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für GPN1 Antikörper (ABIN6937346)

Target: GPN1 (GPN-Loop GTPase 1 (GPN1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GPN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: GPN1-2350

Produktdetails anti-GPN1 Antikörper

Verwendungszweck: GPN1 / XAB1 (DNA Repair & Protein Synthesis) Antibody

Spezifität: GPN1 is involved in protein synthesis events. It is expressed ubiquitously with highest expression in testis. It binds to the RNA polymerase II- (Poll II) associated proteins RPAP1-3 and to XPA (a protein involved in DNA repair mechanisms), thereby forming an interface with Poll II. Via this interaction, GPN1 is thought to mediate the involvement of Pol II in both protein complex formation and protein chaperone/ scaffolding activities. In addition, GPN1 interacts with components of the integrator and molecular chaperone complexes, further implicating GPN1 in protein assembly. GPN1 contains a cluster of acidic amino acids in its C-terminal region and a series of sequences similar to those found in GTP-binding proteins in its N-terminal region, suggesting that GPN1 has possible GTPase activity.

Kreuzreaktivität (Details): Human.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human GPN1 protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: ELISA (For coating, order antibody without BSA), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: Pancreas, Testis, Thyroid or Bladder.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu GPN1

Target: GPN1 (GPN-Loop GTPase 1 (GPN1))

Andere Bezeichnung: GPN1

Hintergrund:

ATP(GTP) binding protein (ATPBD1A), GPN-loop GTPase 1, GPN1, MBD2-interacting protein (MBDin), NTPBP, RNA polymerase II associated protein 4 (RPAP4), XPA-binding protein 1 (XAB1) GTPase

Pancreas, Testis, Thyroid or Bladder.

Molekulargewicht: 42kDa

Gen-ID: 11321, 18259

UniProt: Q9HCN4