CGB Antikörper

Produktnummer ABIN6939105

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CGB in IHC (fro). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CGB Antikörper (ABIN6939105)

Target: CGB (Chorionic Gonadotropin, beta Polypeptide (CGB))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CGB Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: HCGb-211

Produktdetails anti-CGB Antikörper

Spezifität: This MAb reacts with a protein of 22 kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90 % and 60 % of cases respectively. 20 % of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.

Kreuzreaktivität (Details): Human,

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Purified human HCG-beta

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Positive Control: Placenta.

Known Application: Immunohistochemistry (Frozen) (1-2 μg/mL for 30 minutes at RT) Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

Haltbarkeit: 24 months

Details zu CGB

Target: CGB (Chorionic Gonadotropin, beta Polypeptide (CGB))

Andere Bezeichnung: CGB

Hintergrund: CG-beta, CGB3, CGB5, CGB7, CGB8, Choriogonadotropin Subunit beta, hCGB,HCG-beta (Pregnancy & Choriocarcinoma Marker)
Cellular localisation: Cytoplasmic, secreted

Molekulargewicht: 22kDa

Gen-ID: 1082, 172944

UniProt: P01233