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Rekombinanter CEACAM5 Antikörper

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch CEACAM5 in IHC (f). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN6939079

Kurzübersicht für Rekombinanter CEACAM5 Antikörper (ABIN6939079)

Target

Alle CEACAM5 Antikörper anzeigen
CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Antikörpertyp

Recombinant Antibody

Reaktivität

  • 143
  • 20
  • 4
  • 4
  • 1
Human

Wirt

  • 94
  • 45
  • 6
Kaninchen

Klonalität

  • 106
  • 35
  • 2
Monoklonal

Konjugat

  • 77
  • 12
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CEACAM5 Antikörper ist unkonjugiert

Applikation

  • 85
  • 76
  • 57
  • 48
  • 34
  • 25
  • 11
  • 9
  • 8
  • 6
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Klon

C66-1983R
  • Spezifität

    This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70 % are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

    Kreuzreaktivität (Details)

    Human,

    Aufreinigung

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    Immunogen

    Recombinant full-length human CEA protein

    Isotyp

    IgG
  • Applikationshinweise

    Positive Control: MCF7 or 293T cells. Human colon carcinoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    200 μg/mL

    Buffer

    Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

    Haltbarkeit

    24 months
  • Target

    CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

    Andere Bezeichnung

    CEACAM5

    Hintergrund

    Carcinoembryonic Antigen-related Cell Adhesion Molecule 5, CEACAM5, CD66, Biliary Glycoprotein (BGP-1),Carcinoembryonic Antigen (CEA) / CD66
    Cellular localisation: Cytoplasmic and luminal surface

    Molekulargewicht

    80-200kDa

    Gen-ID

    1048, 709196

    UniProt

    P06731
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