TUBB3 Antikörper (AA 437-450)

Produktnummer ABIN6939054

Dieses Anti-TUBB3-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von TUBB3 in WB und IHC (f). Geeignet für Human und Synthetic.

Kurzübersicht für TUBB3 Antikörper (AA 437-450) (ABIN6939054)

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Reaktivität: Human, Synthetic

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TUBB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Klon: TUBB3-3731

Produktdetails anti-TUBB3 Antikörper

Bindungsspezifität: AA 437-450

Spezifität: This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3.In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation.

Kreuzreaktivität (Details): Human. Others not known.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: A synthetic peptide (aa 437-450) of human Tubulin beta 3 protein (TUBB3), coupled to KLH.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Positive Control: U87, A375, Raji, HEP2 cells. Brain and Testis

Known Application: Western Blotting (1-2 μg/mL),Immunohistology (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

Haltbarkeit: 24 months

Details zu TUBB3

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Andere Bezeichnung: TUBB3

Hintergrund: Beta 3 tubulin, CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, M(beta)3, M(beta)6, MC1R, Neuron specific beta III Tubulin, Neuron-specific class III beta-tubulin, TUBB3, TUBB4, Tubulin beta-3, Tubulin beta-4, Tubulin beta-III,Tubulin beta 3 / TUBB3 (Neuronal & Stem Cell Marker)
Cellular localisation: Cytoplasmic

Molekulargewicht: 55kDa

Gen-ID: 10381, 511743

UniProt: Q13509

Pathways: Microtubule Dynamics, M Phase