YWHAE Antikörper

Produktnummer ABIN6938792

Dieser Maus Monoklonal Antikörper detektiert spezifisch YWHAE in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Meerschweinchen und Hamster.

Kurzübersicht für YWHAE Antikörper (ABIN6938792)

Target: YWHAE (14-3-3 epsilon (YWHAE))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Hamster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser YWHAE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: CPTC-YWHAE-1

Produktdetails anti-YWHAE Antikörper

Verwendungszweck: 14-3-3E / Tryptophan 5-Monooxygenase Antibody

Spezifität: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3E has also been identified as a possible susceptibility gene for schizophrenia.

Kreuzreaktivität (Details): Human.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human full-length YWHAE protein

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: HEK-293 or A-431 cell lines.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu YWHAE

Target: YWHAE (14-3-3 epsilon (YWHAE))

Andere Bezeichnung: YWHAE

Hintergrund:

MDS, epididymis luminal protein 2, mitochondrial import stimulation factor (MSF) L subunit, Mitochondrial import stimulation factor L subunit, MSF L, protein kinase C inhibitor protein-1

HEK-293 or A-431 cell lines. Human Brain, Mouse Brain, Rat Brain, Hamster Brain, Guinea pig Brain, Human Lungs, Mouse Lungs, Rat Lungs, Hamster Lungs or Guinea pig Lungs

Molekulargewicht: 29.4kDa

Gen-ID: 7531, 513851

UniProt: P62258

Pathways: Neurotrophin Signalübertragung, Myometrial Relaxation and Contraction, M Phase