YWHAE Antikörper

Produktnummer ABIN6938792

Produktdetails anti-YWHAE Antikörper

Target: YWHAE (14-3-3 epsilon (YWHAE))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser YWHAE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Spezifität: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3E has also been identified as a possible susceptibility gene for schizophrenia.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant human full-length YWHAE protein

Klon: CPTC-YWHAE-1

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: HEK-293 or A-431 cell lines.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu YWHAE

Target: YWHAE (14-3-3 epsilon (YWHAE))

Andere Bezeichnung: YWHAE (YWHAE Produkte)

Synonyme: 14-3-3 antikoerper, 14-3-3 epsilon antikoerper, 14-3-3-e antikoerper, 14-3-3-epsilon antikoerper, 14-3-30epsilon antikoerper, 14-3-3EPSILON antikoerper, 14-3-3e antikoerper, 14-3-3omicron antikoerper, 1433epsilon antikoerper, 143E_DROME antikoerper, CG31196 antikoerper, CT24092 antikoerper, D14-3-3e antikoerper, D14-3-3epsilon antikoerper, Dmel\\CG31196 antikoerper, EK3-5 antikoerper, PAR-5 antikoerper, PAR5 antikoerper, Par-5 antikoerper, SR3-9 antikoerper, Su(Raf)3B antikoerper, anon-WO0172774.141 antikoerper, anon-WO02059370.52 antikoerper, d14-3-3epsilon antikoerper, eps antikoerper, l(3)j2B10 antikoerper, par-5 antikoerper, 14-3-3epsilon antikoerper, kcip-1 antikoerper, mdcr antikoerper, mds antikoerper, LOC581376 antikoerper, Ywhae antikoerper, ACYPI002517 antikoerper, YWHAE antikoerper, 14-3-3E antikoerper, KCIP-1 antikoerper, MDCR antikoerper, MDS antikoerper, AU019196 antikoerper, fe38c12 antikoerper, wu:fb48f06 antikoerper, wu:fe38c12 antikoerper, wu:fi22e10 antikoerper, ywhae antikoerper, zgc:55377 antikoerper, zgc:77062 antikoerper, CG31196 gene product from transcript CG31196-RD antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon antikoerper, 14-3-3 epsilon antikoerper, 14-3-3 epsilon protein antikoerper, 14-3-3 protein epsilon antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon S homeolog antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 antikoerper, 14-3-3epsilon antikoerper, ywhae antikoerper, LOC581376 antikoerper, Ywhae antikoerper, HCAG_04173 antikoerper, PTRG_02836 antikoerper, PTRG_04459 antikoerper, UREG_07864 antikoerper, YWHAE antikoerper, ywhae.S antikoerper, ywhae1 antikoerper

Hintergrund: MDS, epididymis luminal protein 2, mitochondrial import stimulation factor (MSF) L subunit, Mitochondrial import stimulation factor L subunit, MSF L, protein kinase C inhibitor protein-1,14-3-3E / Tryptophan 5-Monooxygenase
Cellular localisation: Cytoplasm. Melanosome.

Molekulargewicht: 29.4kDa

Gen-ID: 7531, 513851

UniProt: P62268

Pathways: Neurotrophin Signalübertragung, Myometrial Relaxation and Contraction, M Phase