YBX1 Antikörper
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- Target Alle YBX1 Antikörper anzeigen
- YBX1 (Y Box Binding Protein 1 (YBX1))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser YBX1 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Spezifität
- The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Y-box binding protein-1 (YBX1) is the prototypic member of the cold shock protein family that fulfills numerous cellular functions. In the nucleus, YBX1 protein orchestrates transcription of proliferation-related genes, whereas in the cytoplasm it associates with mRNA and directs translation. In human tumor entities, such as breast, lung and prostate cancer, cellular YBX1 expression indicates poor clinical outcome, suggesting that YBX1 is an attractive marker to predict patients' prognosis.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant human full-length YBX1 protein
- Klon
- YBX1-2430
- Isotyp
- IgG2b kappa
- Top Product
- Discover our top product YBX1 Primärantikörper
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- Applikationshinweise
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: MCF-7, HEK293 or PC12 cells. Prostate, Breast or Lung Carcinoma.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- YBX1 (Y Box Binding Protein 1 (YBX1))
- Andere Bezeichnung
- YBX1 (YBX1 Produkte)
- Synonyme
- BP-8 antikoerper, CSDA2 antikoerper, CSDB antikoerper, DBPB antikoerper, MDR-NF1 antikoerper, NSEP-1 antikoerper, NSEP1 antikoerper, YB-1 antikoerper, YB1 antikoerper, Byb1 antikoerper, Cbfa antikoerper, Dbpb antikoerper, Ef1a antikoerper, Msy1 antikoerper, Nsep1 antikoerper, Yb1 antikoerper, bp-8 antikoerper, csda2 antikoerper, csdb antikoerper, dbpb antikoerper, frgy1 antikoerper, mdr-nf1 antikoerper, nsep-1 antikoerper, nsep1 antikoerper, yb1 antikoerper, 1700102N10Rik antikoerper, C79409 antikoerper, EF1A antikoerper, MSY1 antikoerper, dbpB antikoerper, mYB-1a antikoerper, nuclease sensitive element binding protein 1 antikoerper, Y-box binding protein 1 antikoerper, Y box binding protein 1 antikoerper, Y-box binding protein 1 S homeolog antikoerper, nuclease-sensitive element-binding protein 1 antikoerper, Y box protein 1 antikoerper, nsep1 antikoerper, YBX1 antikoerper, Ybx1 antikoerper, ybx1.S antikoerper, LOC479011 antikoerper
- Hintergrund
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BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1,YBX1 / Y-box Binding Protein 1 / YB-1 (Tumor Biomarker)
Cellular localisation: Cytoplasmic and Nuclear - Molekulargewicht
- 36kDa
- Gen-ID
- 4904, 473583
- UniProt
- P67809
- Pathways
- Regulation of Muscle Cell Differentiation
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