S100A2 Antikörper

Produktnummer ABIN6938332

Dieses Anti-S100A2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von S100A2 in WB, IF, FACS und IHC (f). Geeignet für Human.

Kurzübersicht für S100A2 Antikörper (ABIN6938332)

Target: S100A2 (S100 Calcium Binding Protein A2 (S100A2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser S100A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Klon: CPTC-S100A2-2

Produktdetails anti-S100A2 Antikörper

Spezifität: S100A2 belongs to the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100A2 may function as a modulator against excess calcium accumulation in normal human mammary epithelial cells and also have a role in suppressing tumor cell growth. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. Cytoplasmic overexpression may also be of prognostic significance when observed in oral cancer patients, and the S100A2 has also been identified as significantly down-regulated in gastric cancer.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human S100A2 protein

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Western Blot (1-2 μg/mL), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: HeLa. A549, HACAT, BxPC3 and A431 cell lysates, Skin and squamous cell cervical carcinoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu S100A2

Target: S100A2 (S100 Calcium Binding Protein A2 (S100A2))

Andere Bezeichnung: S100A2

Hintergrund: CAN19, MGC111539, S100L,S100A2 / S100 Calcium Binding Protein A2
Cellular localisation: Nucleus and cytoplasm.

Molekulargewicht: 11.12kDa

Gen-ID: 6273, 516484

UniProt: P29034

Pathways: S100 Proteine