PAX5 Antikörper
Kurzübersicht für PAX5 Antikörper (ABIN6938117)
Target
Alle PAX5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- The PAX5 gene is a member of thepaired box (PAX)family of transcription factors. The central feature of this gene family is a novel, highly conservedDNA-binding domain, known as thepaired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute toneoplastic transformation. The PAX5 gene encodes theB-celllineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development andspermatogenesis.
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Kreuzreaktivität (Details)
- Human.
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Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogen
- Recombinant full-length human PAX5 protein
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Isotyp
- IgG1 kappa
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Applikationshinweise
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Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.
Positive_Control: Daudi or Ramos cells. Tonsil, spleen, Lymph Node or Colon Carcinoma.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Haltbarkeit
- 24 months
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- PAX5 (Paired Box 5 (PAX5))
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Andere Bezeichnung
- PAX5
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Hintergrund
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B cell lineage specific activator, BSAP, EBB-1, KLP, Paired box 5,PAX5 / BSAP (Early B-Cell Marker)
Cellular localisation: Nuclear -
Molekulargewicht
- 42kDa
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Gen-ID
- 5079, 654464
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UniProt
- Q02548
Target
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