Rekombinanter NEFL Antikörper
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- Target Alle NEFL Antikörper anzeigen
- NEFL (Neurofilament, Light Polypeptide (NEFL))
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser NEFL Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Spezifität
- This MAb reacts with a 68 kDa protein, identified as light sub-unit of neurofilaments (NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
- Kreuzreaktivität (Details)
- Human. Rat. Pig. Cow. Chicken. Dog
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human NEFL protein
- Klon
- NEFL-2983R
- Isotyp
- IgG
- Top Product
- Discover our top product NEFL Primärantikörper
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- Applikationshinweise
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Known_Application: Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Brain, Neuroblastoma.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- NEFL (Neurofilament, Light Polypeptide (NEFL))
- Andere Bezeichnung
- NEFL (NEFL Produkte)
- Synonyme
- NEFL antikoerper, nefl antikoerper, zgc:136626 antikoerper, AI847934 antikoerper, CMT2E antikoerper, NF-L antikoerper, NF68 antikoerper, Nfl antikoerper, CMT1F antikoerper, NFL antikoerper, XNF-L antikoerper, neurofilament light antikoerper, neurofilament, light polypeptide antikoerper, neurofilament, light polypeptide b antikoerper, neurofilament, light L homeolog antikoerper, NEFL antikoerper, neflb antikoerper, Nefl antikoerper, nefl.L antikoerper
- Hintergrund
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68 kDa neurofilament protein, Light molecular weight neurofilament protein, NEFL, Neurofilament light polypeptide 68 kDa, Neurofilament light polypeptide, Neurofilament protein, light chain, Neurofilament subunit NF-L, Neurofilament triplet L protein, NF-L, NF68,Neurofilament (NF-L) (Neuronal Marker)
Cellular localisation: Cytoplasmic - Molekulargewicht
- 68kDa
- Gen-ID
- 4747, 521461
- UniProt
- P07196
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