MMP2 Antikörper (AA 444-575)
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- Target Alle MMP2 Antikörper anzeigen
- MMP2 (Matrix Metalloproteinase 2 (MMP2))
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Bindungsspezifität
- AA 444-575
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser MMP2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- It recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant human MMP2 protein fragment (aa 444-575) (exact sequence is proprietary)
- Klon
- MMP2-1501
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product MMP2 Primärantikörper
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- Applikationshinweise
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Known_Application: Western Blot (1-2 μg/mL) Optimal dilution for a specific application should be determined.
Positive_Control: U-138 MG or U-87 MG cells. Placenta or Colon Carcinoma.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- MMP2 (Matrix Metalloproteinase 2 (MMP2))
- Andere Bezeichnung
- MMP2 (MMP2 Produkte)
- Synonyme
- 2-MMP antikoerper, CG1794 antikoerper, DM2-MMP antikoerper, Dm2-MMP antikoerper, Dmel\\CG1794 antikoerper, MMP2 antikoerper, anon-WO0118547.84 antikoerper, dm-2MMP antikoerper, dmmp2 antikoerper, l(2)02353 antikoerper, mmp2 antikoerper, wu:fa99h12 antikoerper, wu:fk89d01 antikoerper, fgmmp-2 antikoerper, Mmp-2 antikoerper, LOC100135793 antikoerper, Clg4a antikoerper, GelA antikoerper, MMP-2 antikoerper, CLG4 antikoerper, CLG4A antikoerper, MMP-II antikoerper, MONA antikoerper, TBE-1 antikoerper, matrix metallopeptidase 2 antikoerper, Matrix metalloproteinase 2 antikoerper, matrix metalloproteinase 2 antikoerper, matrix metalloproteinase-2 antikoerper, MMP2 antikoerper, Mmp2 antikoerper, mmp2 antikoerper, LOC657982 antikoerper, LOC100135793 antikoerper
- Hintergrund
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72kD type IV collagenase, CLG4A, Collagenase Type 4 alpha, Collagenase type IV A, Gelatinase A, Gelatinase alpha, Gelatinase neutrophil, Matrix metalloproteinase-2, MMP2, MONA, Neutrophil gelatinase, PEX, TBE-1,MMP2 / Collagenase Type IV A (Tumor Metastasis Marker)
Cellular localisation: Cytoplasmic and Cell Surface - Molekulargewicht
- 72kDa (Pro), 63kDa (cleaved)
- Gen-ID
- 4313, 513617
- UniProt
- P08253
- Pathways
- Activation of Innate immune Response
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