Rekombinanter Mammaglobin A Antikörper

Produktnummer ABIN6937804

Dieses Anti-Mammaglobin A-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von Mammaglobin A in IHC (f). Geeignet für Human.

Kurzübersicht für Rekombinanter Mammaglobin A Antikörper (ABIN6937804)

Target: Mammaglobin A (SCGB2A2) (Secretoglobin, Family 2A, Member 2 (SCGB2A2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Mammaglobin A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Klon: MGB1-2123R

Produktdetails anti-Mammaglobin A Antikörper

Spezifität: Mammaglobin is a 93 amino acid glycoprotein with homology to other secretoglobin-uteroglobin family members. It was originally identified as a breast cancer restricted biomarker by differential screening. Mammaglobin related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin antibody stains cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas. Mammaglobin expression is absent in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung, and thyroid tissues.Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human SCGB2A2 (Mammaglobin-1) protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or MCF-7 cells. Mammary gland specific. Overexpressed in breast cancer.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu Mammaglobin A

Target: Mammaglobin A (SCGB2A2) (Secretoglobin, Family 2A, Member 2 (SCGB2A2))

Andere Bezeichnung: Mammaglobin (SCGB2A2) (Breast Cancer Marker)

Hintergrund: Mammaglobin-1 (MGB1), Mammaglobin-A, Secretoglobin family 2A member 2 (SCGB2A2), SG2A2, UGB2,Mammaglobin (SCGB2A2) (Breast Cancer Marker)
Cellular localisation: Cytoplasmic expression in ductal cells. Additional plasma positivity in lactating breast.

Molekulargewicht: 18kDa

Gen-ID: 4250, 46452

UniProt: Q13296