LMO2 Antikörper (AA 23-140)

Produktnummer ABIN6937789

Produktdetails anti-LMO2 Antikörper

Target: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Bindungsspezifität: AA 23-140

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LMO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Spezifität: The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma.The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin. LMO2 is useful in differentiating follicular lymphoma (LMO2+) from nodal marginal zone lymphoma (LM02-). It also is positive in Hodgkin s and Burkitt s lymphomas.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant human LMO2 protein fragment (around aa 23-140) (exact sequence is proprietary)

Klon: LMO2-1971

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: K562, Ramos or Raji cells. Placenta, pancreas or Hodgkin s lymphoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu LMO2

Target: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Andere Bezeichnung: LMO2 (LMO2 Produkte)

Synonyme: Rbtn-2 antikoerper, Rbtn2 antikoerper, Rhom-2 antikoerper, Ttg2 antikoerper, RBTN2 antikoerper, RBTNL1 antikoerper, RHOM2 antikoerper, TTG2 antikoerper, wu:fc83a08 antikoerper, zgc:111930 antikoerper, LMO-2 antikoerper, lmo2-A antikoerper, xlmo2 antikoerper, rhombotin-2 antikoerper, LIM domain only 2 antikoerper, LIM domain only 2 (rhombotin-like 1) antikoerper, LIM domain only 2 S homeolog antikoerper, lmo2 antikoerper, LMO2 antikoerper, Lmo2 antikoerper, lmo2.S antikoerper

Hintergrund: Cysteine-rich protein TTG-2, LIM domain only protein 2, LMO-2, RBTN L1, RBTN2, Rhombotin like 1, Rhombotin-2 (RHOM2), T-cell translocation protein 2, TTG2,LMO2 (B-Cell Marker)
Cellular localisation: Nuclear

Molekulargewicht: 24kDa

Gen-ID: 4005, 34560

UniProt: P25791

Pathways: Chromatin Binding