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KRT Antikörper

KRT126P Reaktivität: Human FACS, IHC, IF, IHC (f) Wirt: Maus Monoclonal PCK-3150 unconjugated
Produktnummer ABIN6937638
  • Target Alle KRT (KRT126P) Produkte
    KRT (KRT126P) (Keratin 126 Pseudogene (KRT126P))
    Reaktivität
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 4
    • 3
    Maus
    Klonalität
    • 5
    • 2
    Monoklonal
    Konjugat
    • 7
    Dieser KRT Antikörper ist unkonjugiert
    Applikation
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Spezifität
    Anti-cytokeratin clone PCK/3150 demonstrates a broad spectrum of cytokeratin reactivity. In normal tissues, PCK/3150 is reactive with most epithelial types, including bile ducts and hepatocytes in liver, bladder epithelium, breast ducts, bronchial epithelium, endometrium, intestinal epithelium of stomach, duodenum, ileum, colon, rectum, pancreas, ovarian epithelium, pancreatic acini, pituitary acini, pneumocytes, prostate, thyroid, skin (positive on the basal layer and negative on the superficial layers of squamous epithelium), and apocrine and sweat glands. In tumors, PCK/3150 is reactive with most carcinomas, including breast, transitional cell (TCC), renal cell (RCC), lung adenocarcinoma, lung small cell, lung squamous cell, endometrial, prostate, ovarian, hepatocellular (HCC), colorectal CA, stomach and thyroid. It is negative in certain normal tissues, including brain, lymphocytes and all cells of hematolymphoid origin, muscle, brain, nerves, endothelium and in certain tumors including most melanomas, sarcomas, lymphomas, primitive neuroectodermal tumors (PNET)/Ewings and gastrointestinal stromal tumors (GIST). Positivity has been seen on some dendritic cells in lymph nodes, some endothelia, and some muscle cells.
    Kreuzreaktivität (Details)
    Human. Dog. Cat.
    Aufreinigung
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Crude cytokeratin extract prepared from RT-4 and MCF-7 cells.
    Klon
    PCK-3150
    Isotyp
    IgG2a kappa
  • Applikationshinweise

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Skin, adeno- or squamous carcinomas (IHC).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Haltbarkeit
    24 months
  • Target
    KRT (KRT126P) (Keratin 126 Pseudogene (KRT126P))
    Andere Bezeichnung
    KRT (KRT126P Produkte)
    Synonyme
    KRT antikoerper, keratin 126 pseudogene antikoerper, KRT126P antikoerper
    Hintergrund
    K1B, KRT1B, Keratin, type II cytoskeletal 1b, K77, CK-1B, Keratin 1B, Keratin-77, Cytokeratin-1B, Type-II Keratin Kb39,Cytokeratin, pan (Epithelial Marker)
    Cellular localisation: Cytoplasmic
    Molekulargewicht
    40-67kDa (Multiple)
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