IL7R Antikörper (AA 21-236)

Produktnummer ABIN6937563

Produktdetails anti-IL7R Antikörper

Target: IL7R (Interleukin 7 Receptor (IL7R))

Bindungsspezifität: AA 21-236

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL7R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Coating (Coat)

Spezifität: The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID).

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant fragment (around aa 21-236) of human CD127 protein (IL7R) (exact sequence is proprietary)

Klon: IL7R-2751

Isotyp: IgG2c kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: ELISA (For coating, order Ab without BSA),Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: K562, HeLa, Daudi or Jurkat cells. Tonsil, Lymph Node or Spleen.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu IL7R

Target: IL7R (Interleukin 7 Receptor (IL7R))

Andere Bezeichnung: IL7R (IL7R Produkte)

Synonyme: IL7R antikoerper, CD127 antikoerper, IL-7Ralpha antikoerper, CDW127 antikoerper, IL-7R-alpha antikoerper, IL7RA antikoerper, ILRA antikoerper, IL-7RA antikoerper, interleukin 7 receptor antikoerper, IL7R antikoerper, Il7r antikoerper

Hintergrund: CD127, IL-7 receptor subunit alpha, IL-7R-alpha, IL7R, IL7RA, IL7R alpha, ILRA, Interleukin 7 receptor alpha chain, Interleukin 7 receptor,CD127 / IL7R (Marker of T-Reg Cells)
Cellular localisation: Cell Surface and Cytoplasmic

Molekulargewicht: 52-72kDa

Gen-ID: 3575, 591742, 635723

UniProt: P16871

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size