IGKC Antikörper

Produktnummer ABIN6937529

Dieser Maus Monoklonal Antikörper detektiert spezifisch IGKC in IHC und FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für IGKC Antikörper (ABIN6937529)

Target: IGKC (Immunoglobulin kappa Constant (IGKC))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IGKC Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Flow Cytometry (FACS)

Klon: SPM508

Produktdetails anti-IGKC Antikörper

Verwendungszweck: Kappa Light Chain (B-Cell Marker) Antibody

Spezifität: This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Keine Kreuzreaktivität: Ratte (Rattus)

Kreuzreaktivität (Details): Human. Does not react with Rat.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Human B-Lymphoma Cells

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Flow Cytometry (0.5-2.0 μg/million cells), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: 293T, Raji or hPBL cells. Tonsil or Spleen.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu IGKC

Target: IGKC (Immunoglobulin kappa Constant (IGKC))

Andere Bezeichnung: IGKC

Hintergrund:

HCAK1, Ig Kappa Chain C Region, IGKC, Immunoglobulin KM

293T, Raji or hPBL cells. Tonsil or Spleen.

Molekulargewicht: ~22.5kDa

Gen-ID: 3514, 449609

UniProt: P01601