IGKC Antikörper

Produktnummer ABIN6939745

Dieser Maus Monoklonal Antikörper detektiert spezifisch IGKC in IHC, WB, FACS und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für IGKC Antikörper (ABIN6939745)

Target: IGKC (Immunoglobulin kappa Constant (IGKC))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IGKC Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: KLC264

Produktdetails anti-IGKC Antikörper

Verwendungszweck: Kappa Light Chain (B-Cell Marker) Antibody

Spezifität: This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human Ig kappa chain

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: 293T, Raji or hPBL cells. Tonsil or Spleen.

Known Application: Western Blot (1-2 μg/mL), Flow Cytometry (1-2 μg/million cells), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu IGKC

Target: IGKC (Immunoglobulin kappa Constant (IGKC))

Andere Bezeichnung: IGKC

Hintergrund:

HCAK1, Ig Kappa Chain C Region, IGKC, Immunoglobulin KM

293T, Raji or hPBL cells. Human tonsil or spleen.

Molekulargewicht: ~22.5kDa

Gen-ID: 3514, 449609

UniProt: P01601