IGHM Antikörper
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- Target Alle IGHM Produkte
- IGHM (Immunoglobulin Heavy Constant mu (IGHM))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser IGHM Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Spezifität
- Recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin s lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant heavy chain of human IgM
- Klon
- IM260
- Isotyp
- IgG1 kappa
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- Applikationshinweise
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Known_Application: Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: 293T, Raji or hPBL cells. Human tonsil or spleen (IHC).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- IGHM (Immunoglobulin Heavy Constant mu (IGHM))
- Andere Bezeichnung
- IGHM (IGHM Produkte)
- Synonyme
- AI326478 antikoerper, Igh-6 antikoerper, Igh-M antikoerper, Igh6 antikoerper, Igm antikoerper, muH antikoerper, ighm1 antikoerper, wu:fj14a08 antikoerper, zgc:101769 antikoerper, AGM1 antikoerper, MU antikoerper, VH antikoerper, immunoglobulin heavy constant mu antikoerper, Ighm antikoerper, ighm antikoerper, IGHM antikoerper
- Hintergrund
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AGM1, IGHM, Constant Region of Heavy Chain of IgM, Ig Mu Chain C Region,IgM (Immunoglobulin Mu Heavy Chain) (B-Cell Marker)
Cellular localisation: Cytoplasm, Cell Surface and Secreted - Molekulargewicht
- 50-75kDa
- Gen-ID
- 3507, 510635
- UniProt
- P01871, P20769
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