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Rekombinanter Frataxin Antikörper (AA 57-210)

FXN Reaktivität: Human ELISA, Coat Wirt: Maus Monoclonal rFXN-2124 unconjugated Recombinant Antibody

Produktnummer ABIN6937290

Datenblatt (PDF)

Target Alle Frataxin (FXN) Antikörper anzeigen

Frataxin (FXN)

Antikörpertyp

Recombinant Antibody
Bindungsspezifität
9

8

7

6

5

4

3

3

2

2

1

1

1

1

1
AA 57-210
Reaktivität
61

21

12

3

3

3

2

2

2

2

1

1

1

1
Human
Wirt
53

17
Maus
Passende Sekundärantikörper
Klonalität
55

15
Monoklonal
Konjugat
44

5

5

4

3

3

1

1

1

1

1

1
Dieser Frataxin Antikörper ist unkonjugiert
Applikation
55

34

25

11

6

3

2

2

1

1

1

1

1

1

1

1

1
ELISA, Coating (Coat)

Spezifität

Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.

Kreuzreaktivität (Details)

Human.

Aufreinigung

1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen

Recombinant human Frataxin protein fragment (around aa 57-210) (exact sequence is proprietary)

Klon

RFXN-2124

Isotyp

IgG1 kappa

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anti-Frataxin (FXN) (AA 1-210) antibody
FXN Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated

Applikationshinweise

Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA),Optimal dilution for a specific application should be determined.
Positive_Control: HepG2, HL-60 or HEK293 cells. Pancreas and Liver.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Buffer

Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel

Azide free

Lagerung

-20 °C,-80 °C

Informationen zur Lagerung

Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit

24 months
Target

Frataxin (FXN)

Andere Bezeichnung

FXN (FXN Produkte)

Hintergrund

CyaY, d-FXN, FARR, Frataxin mature form, Frataxin (81-210), FRDA, Friedreich ataxia protein, Fxn, i-FXN, m56-FXN, m78-FXN, m81-FXN, X25,Frataxin (Mitochondrial Marker)
Cellular localisation: Cytoplasmic (Mitochondria)

Molekulargewicht

14kDa

Gen-ID

2395, 20685

UniProt

Q16595

Pathways

Transition Metal Ion Homeostasis, Regulation of Cell Size