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FSHB Antikörper

FSHB Reaktivität: Human IHC (f) Wirt: Maus Monoclonal FSHb-1062 unconjugated
Produktnummer ABIN6937268
  • Target Alle FSHB Antikörper anzeigen
    FSHB (Follicle Stimulating Hormone, beta Polypeptide (FSHB))
    Reaktivität
    • 81
    • 27
    • 15
    • 7
    • 1
    • 1
    • 1
    Human
    Wirt
    • 56
    • 38
    Maus
    Klonalität
    • 55
    • 39
    Monoklonal
    Konjugat
    • 41
    • 9
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FSHB Antikörper ist unkonjugiert
    Applikation
    • 60
    • 49
    • 21
    • 13
    • 13
    • 11
    • 10
    • 9
    • 8
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Spezifität
    This MAb reacts with a protein of 22 kDa, identified as beta sub-unit of FSH. It does not cross react with the alpha sub-unit. Follicle stimulating hormone (FSH) is a hormone synthesized and secreted by gonadotrophs in the anterior pituitary gland. In the ovary, FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows, it releases inhibin, which deactivates the FSH production. In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testis and is critical for spermatogenesis. FSH and LH act synergistically in reproduction. FSH is a useful marker in the classification of pituitary tumors and the study of pituitary disease.
    Kreuzreaktivität (Details)
    Human.
    Aufreinigung
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant full-length hFSH beta sub-unit
    Klon
    FSHb-1062
    Isotyp
    IgG1 kappa
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  • Applikationshinweise

    Known_Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Anterior Pituitary.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Haltbarkeit
    24 months
  • Target
    FSHB (Follicle Stimulating Hormone, beta Polypeptide (FSHB))
    Andere Bezeichnung
    FSHB (FSHB Produkte)
    Synonyme
    gthI antikoerper, fsh-beta antikoerper, LOC100136594 antikoerper, FSHB antikoerper, LOC100218526 antikoerper, FSH antikoerper, Fshbeta antikoerper, FSH-beta antikoerper, follicle stimulating hormone, beta polypeptide antikoerper, follicle stimulating hormone beta subunit L homeolog antikoerper, follcle-stimulating hormone beta subunit antikoerper, follicle stimulating hormone beta subunit antikoerper, follicle stimulating hormone beta antikoerper, follitropin subunit beta antikoerper, fshb antikoerper, fshb.L antikoerper, LOC100136594 antikoerper, FSHB antikoerper, Fshb antikoerper
    Hintergrund
    Follicle stimulating hormone beta polypeptide, Follicle stimulating hormone beta subunit, Follitropin beta chain, Follitropin subunit beta, FSH-B, FSH-beta, FSHB, FSHbeta,FSH-beta (Follicle Stimulating Hormone-beta)
    Cellular localisation: Cytoplasmic, secreted
    Molekulargewicht
    22kDa
    Gen-ID
    2488, 36975
    UniProt
    P01225
    Pathways
    Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process
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