FLT1 Antikörper

Produktnummer ABIN6937237

Produktdetails anti-FLT1 Antikörper

Target: FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FLT1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Spezifität: Three cell membrane receptor tyrosine kinases, Flt-1 (also designated VEGF-R1), Flk-1 (also designated VEGF-R2) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulin-like sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to Flt-1 and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant human VEGF-R1 protein

Klon: FLT1-658

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Functional Studies (Order Ab without BSA & Azide), Optimal dilution for a specific application should be determined.

Positive_Control: 293FT or A431 cells. Cerebellum or skin cancer.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu FLT1

Target: FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

Andere Bezeichnung: FLT1 (FLT1 Produkte)

Synonyme: FLT antikoerper, FLT-1 antikoerper, VEGFR-1 antikoerper, VEGFR1 antikoerper, FLT1 antikoerper, flt1b antikoerper, sFlt1 antikoerper, AI323757 antikoerper, Flt-1 antikoerper, fms related tyrosine kinase 1 antikoerper, FMS-related tyrosine kinase 1 antikoerper, vascular endothelial growth factor receptor 1 antikoerper, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) antikoerper, FMS-like tyrosine kinase 1 antikoerper, vascular endothelial growth factor receptor-1 antikoerper, FLT1 antikoerper, Flt1 antikoerper, CpipJ_CPIJ012087 antikoerper, flt1 antikoerper, FLT-1 antikoerper

Hintergrund: Fms like tyrosine kinase 1 (Flt-1), Fms-like tyrosine kinase 1, FRT, Tyrosine protein kinase FRT, Tyrosine protein kinase receptor FLT, Vascular endothelial growth factor receptor 1 (VEGFR1), Vascular permeability factor receptor 1,VEGF-R1 / FLT-1
Cellular localisation: Cell surface

Molekulargewicht: 150-180kDa

Gen-ID: 2321, 594454

UniProt: P17948

Pathways: RTK Signalweg, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals