ErbB2/Her2 Antikörper (Intracellular)
Kurzübersicht für ErbB2/Her2 Antikörper (Intracellular) (ABIN6937178)
Target
Alle ErbB2/Her2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- Intracellular
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Verwendungszweck
- HER-2 / c-erbB-2 / neu / CD340 Antibody
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Spezifität
- This MAb is specific to c-erbB-2/HER-2 and shows minimal cross-reaction with other members of the family. C-erbB-2/HER-2 is a member of the EGFR family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
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Kreuzreaktivität (Details)
- Human.
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Aufreinigung
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant intracellular domain of human HER-2 protein
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Isotyp
- IgG1, kappa
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anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 23-372) antibody
ErbB2/Her2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (pTyr1248) antibodyErbB2/Her2 Reaktivität: Human, Maus, Ratte WB, IHC, IF, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (pTyr877) antibodyErbB2/Her2 Reaktivität: Human, Maus, Ratte WB, IHC, IF, ELISA, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (pTyr1112) antibodyErbB2/Her2 Reaktivität: Human, Maus, Ratte WB, IHC, IF, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 22-121) antibodyErbB2/Her2 Reaktivität: Human WB, IF, ELISA, IHC (p), PLA Wirt: Maus Monoclonal 3B1 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (C-Term) antibodyErbB2/Her2 Reaktivität: Human, Maus, Ratte, Hund, Affe, Pferd, Schwein, Rind (Kuh), Kaninchen, Hamster, Avian, Cat, Huhn, Esel, Ziege, Meerschweinchen, Schaf WB, IHC (p), IHC (fro) Wirt: Ziege Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 311-462) antibodyErbB2/Her2 Reaktivität: Human IHC, IF, FACS Wirt: Maus Monoclonal ERBB2-2452 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 311-462) antibodyErbB2/Her2 Reaktivität: Human IHC Wirt: Maus Monoclonal ERBB2-3078 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 1205-1255) antibodyErbB2/Her2 Reaktivität: Human, Maus WB, IHC, FACS, IP, ICC Wirt: Kaninchen Monoclonal BLR241L unconjugated Recombinant Antibody
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (N-Term) antibodyErbB2/Her2 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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Known_Application: ELISA (For coating, order antibody without BSA),Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: MCF-7, SKBR-3 cells. Breast Cancers.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Haltbarkeit
- 24 months
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- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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Andere Bezeichnung
- ERBB2
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Hintergrund
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p185, CD340, Verb b2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog
MCF-7, SKBR-3 cells. Breast Cancers.
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Molekulargewicht
- 185kDa
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Gen-ID
- 2064, 446352
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UniProt
- P04626
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Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Skeletal Muscle Fiber Development
Target
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