CDX2 Antikörper

Produktnummer ABIN6936923

Dieser Maus Monoklonal Antikörper detektiert spezifisch CDX2 in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CDX2 Antikörper (ABIN6936923)

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CDX2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: CDX2-2214

Produktdetails anti-CDX2 Antikörper

Verwendungszweck: CDX2 / Caudal Type Homeobox 2 (GI Epithelial Marker) Antibody

Spezifität: The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoidsand is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma.However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.

Kreuzreaktivität (Details): Human.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human full-length CDX2 protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0 for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Positive_Control: HT29 cells. Colon Carcinoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu CDX2

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Andere Bezeichnung: CDX2

Hintergrund:

Caudal type homeobox 2, Caudal type homeobox transcription factor 2, Caudal-type homeobox protein 2, CDX2

HT29 cells. Colon Carcinoma.

Molekulargewicht: 40kDa

Gen-ID: 1045, 174249

UniProt: Q99626

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance