CD47 Antikörper

Produktnummer ABIN6936738

Der Maus Monoklonal anti-CD47 Antikörper wird verwendet zum Nachweis von CD47 in Proben von Human. Er wurde validiert für FACS, WB, IF und Func.

Kurzübersicht für CD47 Antikörper (ABIN6936738)

Target: CD47

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD47 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Functional Studies (Func)

Klon: B6H12-2

Produktdetails anti-CD47 Antikörper

Verwendungszweck: CD47 / IAP (Integrin Associated Protein) Antibody

Spezifität: This antibody reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

Kreuzreaktivität (Details): Human.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Intact CD47 Purified from placenta

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Functional Studies (Order Ab without Azide), Western Blot (1-2 μg/mL), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: Jurkat, MCF-7 or OVCA3 cells. Human placenta, brain or ovarian tumors.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu CD47

Target: CD47

Andere Bezeichnung: CD47

Hintergrund:

Antigenic Surface Determinant Protein OA3, IAP, Integrin Associated Protein, Integrin Associated Signal Transducer, MER6, OA3, Protein MER6, Rh Related Antigen

brain or ovarian tumors., Jurkat, MCF-7 or OVCA3 cells. Human placenta

Molekulargewicht: ~50kDa

Gen-ID: 961, 446414

UniProt: Q08722